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Chapter 1 - Overview of Autophagy
M.A. Hayat
Pages 1-122 - Book chapterAbstract only
Chapter 2 - The Role of Autophagy in Aging: Molecular Mechanisms
Maria Markaki, Athanasios Metaxakis and Nektarios Tavernarakis
Pages 123-138 - Book chapterAbstract only
Chapter 3 - The Role of p62 in Aggregopathies
Estelle Cormet-Boyaka, Kyle Caution, ... Amal O. Amer
Pages 139-147 - Book chapterAbstract only
Chapter 4 - Role of Autophagy in the Transition From Monocyte to Differentiation
Yan Zhang, Swati Choksi and Zhenggang Liu
Pages 149-159 - Book chapterAbstract only
Chapter 5 - Cdc48 AAA ATPase Regulates Protein Dynamics and Turnover in Mitochondria
Masatoshi Esaki
Pages 161-173 - Book chapterAbstract only
Chapter 6 - Autophagy in Plasma Cells
Niccolò Pengo and Simone Cenci
Pages 175-186 - Book chapterAbstract only
Chapter 7 - Loss of PINK1 or Parkin Function Results in a Progressive Loss of Mitochondrial Function
Jan-Willem Taanman and Margherita Protasoni
Pages 187-209 - Book chapterAbstract only
Chapter 8 - Role of the Transcription Factor Interferon Regulatory Factor-1 in Regulating Autophagy in Lipopolysaccharide-Stimulated Macrophages
Lemeng Zhang and Allan Tsung
Pages 211-230 - Book chapterAbstract only
Chapter 9 - Mechanistic Target of Rapamycin: The Alpha and Omega of Autophagy Regulation
Olivia C. McKee-Muir and Ryan C. Russell
Pages 231-250 - Book chapterAbstract only
Chapter 10 - ER-Phagy in Starvation, ER Stress, and Quality Control
Zhanna Lipatova and Nava Segev
Pages 251-260 - Book chapterAbstract only
Chapter 11 - Role of Autophagy Inhibition in Tumor Proliferative Arrest
Jessie Yanxiang Guo
Pages 261-274 - Book chapterAbstract only
Chapter 12 - Survival at the Brink: Chromatin Autophagy of Tumor Cells in Response to Genotoxic Challenge
Jekaterina Erenpreisa, Kristine Salmiņa, ... Mark S. Cragg
Pages 275-294 - Book chapterAbstract only
Chapter 13 - Loss of Autophagy in Hypothalamic Neurons May Be Involved in the Pathogenesis of Obesity
Yenniffer Ávalos, María Paz Hernández-Cáceres, ... Eugenia Morselli
Pages 295-312 - Book chapterAbstract only
Chapter 14 - Defective Autophagy in Mesenteric Fat Tissue Maintains Inflammation in Crohn’s Disease
Raquel F. Leal and Francesca A. Ramos Silva
Pages 313-323 - Book chapterAbstract only
Chapter 15 - Autophagy Regulates Inflammatory Responses in Antigen-Presenting Cells: Underlying Mechanisms
James Harris, Tali Lang and Maria B. Sukkar
Pages 325-341 - Book chapterAbstract only
Chapter 16 - Autophagy Accompanies Inflammasome Activation to Moderate Inflammation by Eliminating Active Inflammasomes
Neel R. Nabar, Chong-Shan Shi and John H. Kehrl
Pages 343-357 - Book chapterAbstract only
Chapter 17 - Autophagy, Inflammation, and Breast Cancer Risk
Katherine L. Cook and Robert Clarke
Pages 359-372 - Book chapterAbstract only
Chapter 18 - AMBRA1-Mediated Regulation of C-MYC and Its Relevance to Cancer
Valentina Cianfanelli and Francesco Cecconi
Pages 373-385 - Book chapterAbstract only
Chapter 19 - The Delicate Balance of Autophagy in Neurodegeneration
Melissa Nassif, Ute Woehlbier and Patricio A. Manque
Pages 387-399 - Book chapterAbstract only
Chapter 20 - Silibinin Protects Ultraviolet B–Irradiated Skin by Balancing Apoptosis and Autophagy in Epidermis and Dermis
Takashi Ikejima and Toshihiko Hayashi
Pages 401-418 - Book chapterAbstract only
Chapter 21 - Role of Autophagy Activation in Alleviating Alcohol Neurotoxicity
Jia Luo
Pages 419-434 - Book chapterAbstract only
Chapter 22 - Lipopolysaccharide-Enhanced Bactericidal Activity is Mediated by Induction of the Autophagosomal Process
Marc Y. Fink, Matthew R. Weichseldorfer, ... Michelle L. Snyder
Pages 435-449 - Book chapterAbstract only
Chapter 23 - Role of Autophagy in Liver Regeneration
Takeo Toshima, Ken Shirabe, ... Yoshihiko Maehara
Pages 451-461 - Book chapterAbstract only
Chapter 24 - A Dual Role of a Soluble N-Ethylmaleimide Sensitive Factor–Attachment Protein Alpha (αSNAP) in the Regulation of Autophagy
Andrei I. Ivanov
Pages 463-472 - Book chapterAbstract only
Chapter 25 - Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Induces Autophagic Protein Cleavage in Melanoma Cells
Min You, Dao Nguyen, ... Niramol Savaraj
Pages 473-487 - Book chapterNo access
Abbreviations and Glossary
Pages 489-501 - Book chapterNo access
Index
Pages 503-528
About the book
Description
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 12 discusses and details almost all aspects of the autophagy machinery in the context of health, cancer and other pathologies. Autophagy is more widely accepted as beneficial given its role in eliminating ‘toxic assets’ and promoting cell viability, hence, it has emerged as a new and potent modulator of disease progression that is both scientifically intriguing and clinically relevant. As the latest release in the Autophagy book series, users will find a detailed explanation of the role of molecular mechanisms.
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 12 discusses and details almost all aspects of the autophagy machinery in the context of health, cancer and other pathologies. Autophagy is more widely accepted as beneficial given its role in eliminating ‘toxic assets’ and promoting cell viability, hence, it has emerged as a new and potent modulator of disease progression that is both scientifically intriguing and clinically relevant. As the latest release in the Autophagy book series, users will find a detailed explanation of the role of molecular mechanisms.
Key Features
- Presents the most advanced information regarding the role of the autophagic system in life and death
- States recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities
- Summarizes the most up-to-date findings on how autophagy is executed and regulated at the molecular level and how its disruption can lead to disease
- Authored by global leaders in the field, bringing the broadest, most expert coverage available
- Presents the most advanced information regarding the role of the autophagic system in life and death
- States recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities
- Summarizes the most up-to-date findings on how autophagy is executed and regulated at the molecular level and how its disruption can lead to disease
- Authored by global leaders in the field, bringing the broadest, most expert coverage available
Details
ISBN
978-0-12-812146-7
Language
English
Published
2018
Copyright
Copyright © 2018 Elsevier Inc. All rights reserved.
Imprint
Academic Press