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Table of contents
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Chapter One - Introduction: Major Ideas and Historical Perspectives
Pages 1-14 - Book chapterNo access
Chapter Two - DNA Damage
Pages 15-26 - Book chapterNo access
Chapter Three - Immediate Consequences of DNA Damage
Pages 27-36 - Book chapterNo access
Chapter Four - Accumulation of DNA Damage in Somatic Cells
Pages 37-65 - Book chapterNo access
Chapter Five - The DNA Damage Hypothesis of Aging Applied to Mammals
Pages 66-90 - Book chapterNo access
Chapter Six - Oxidative DNA Damage as a Potential Major Cause of Aging
Pages 91-107 - Book chapterNo access
Chapter Seven - Additional Evidence Bearing on the DNA Damage Hypothesis of Aging
Pages 108-151 - Book chapterNo access
Chapter Eight - Aging in Nonmammalian Organisms, with Comparisons to Aspects of Aging in Mammals
Pages 152-172 - Book chapterNo access
Chapter Nine - DNA Repair with Emphasis on Single-Strand Damages
Pages 173-207 - Book chapterNo access
Chapter Ten - DNA Repair with Emphasis on Recombinational Repair
Pages 208-234 - Book chapterNo access
Chapter Eleven - Meiosis and Meiotic Recombination
Pages 235-247 - Book chapterNo access
Chapter Twelve - Meiosis Viewed as an Adaptation for DNA Repair
Pages 248-271 - Book chapterNo access
Chapter Thirteen - The Selective Advantage of Outcrossing
Pages 272-289 - Book chapterNo access
Chapter Fourteen - Evolutionary Aspects of Sex
Pages 290-312 - Book chapterNo access
Chapter Fifteen - Other Theories of Aging and Sex
Pages 313-345 - Book chapterNo access
Chapter Sixteen - Overview, Future Directions, and Implications
Pages 346-371 - Book chapterNo access
Subject Index
Pages 373-382
About the book
Description
Why organisms age and why sexual reproduction exists are major unsolved problems in biology. This book provides an integrated explanation of aging and sex based on current knowledge of DNA damage and repair.
Why organisms age and why sexual reproduction exists are major unsolved problems in biology. This book provides an integrated explanation of aging and sex based on current knowledge of DNA damage and repair.
Key Features
- Discusses the universality of the problem of DNA damage
- Describes aging as a consequence of accumulated DNA damage
- Considers meiosis as an adaptation for DNA repair
- Discusses mating in eukaryotes as an adaptation for masking mutation
- Discusses the universality of the problem of DNA damage
- Describes aging as a consequence of accumulated DNA damage
- Considers meiosis as an adaptation for DNA repair
- Discusses mating in eukaryotes as an adaptation for masking mutation
Details
ISBN
978-0-12-092860-6
Language
English
Published
1991
Copyright
Copyright © 1991 Elsevier Inc. All rights reserved.
Imprint
Academic Press