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Table of contents
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CHAPTER 1 - Introduction
Pages 1-15 - Book chapterNo access
CHAPTER 2 - Acute Toxicology Program: Study Design and Development
Pages 17-30 - Book chapterNo access
CHAPTER 3 - Tests for Dermal Irritation and Corrosion
Pages 31-56 - Book chapterNo access
CHAPTER 4 - Ocular Irritation Testing
Pages 57-84 - Book chapterNo access
CHAPTER 5 - Dermal Sensitization
Pages 85-125 - Book chapterNo access
CHAPTER 6 - Photosensitization and Phototoxicity
Pages 127-153 - Book chapterNo access
CHAPTER 7 - Lethality Testing
Pages 155-196 - Book chapterNo access
CHAPTER 8 - Safety Considerations for the Administration of Agents by the Parenteral Routes
Pages 197-220 - Book chapterNo access
CHAPTER 9 - Systemic Acute Toxicity Testing
Pages 221-256 - Book chapterNo access
CHAPTER 10 - Routes, Formulations, and Vehicles
Pages 257-303 - Book chapterNo access
CHAPTER 11 - Considerations Specific to Animal Test Models
Pages 305-360 - Book chapterNo access
CHAPTER 12 - Statistical Analysis of Acute Toxicology and Safety Studies
Pages 361-402 - Book chapterNo access
CHAPTER 13 - Acute Inhalation
Pages 403-465 - Book chapterNo access
CHAPTER 14 - Problems and Issues
Pages 467-492 - Book chapterNo access
APPENDIX A - Common Regulatory and Toxicological Acronyms
Pages 493-494 - Book chapterNo access
APPENDIX B - Table for Calculation of Median Effective Dose by Moving Average
Pages 495-515 - Book chapterNo access
APPENDIX C - Vehicles
Pages 517-524 - Book chapterNo access
APPENDIX D - Definition of Terms and Lexicon of Clinical Observations
Pages 525-527 - Book chapterNo access
INDEX
Pages 529-534
About the book
Description
Acute toxicology testing provides the first line of defense against potentially dangerous chemicals. This book is a complete and practical guide to conducting and interpreting all regulatory required and commonly used acute toxicity tests. It presents detailed protocols for all of the common test designs and reviews their development and objectives. Acute Toxicology Testing, Second Edition will interest not only workers in the pharmaceutical industry, but also researchers and students in toxicology and public health.
Acute toxicology testing provides the first line of defense against potentially dangerous chemicals. This book is a complete and practical guide to conducting and interpreting all regulatory required and commonly used acute toxicity tests. It presents detailed protocols for all of the common test designs and reviews their development and objectives. Acute Toxicology Testing, Second Edition will interest not only workers in the pharmaceutical industry, but also researchers and students in toxicology and public health.
Key Features
@introbul:Key Features
@bul:* Over 100 tables summarizing and interpreting results
* Complete coverage of all major test designs and their limitations and advantages
* Current status of alternative test designs and models
@introbul:Key Features
@bul:* Over 100 tables summarizing and interpreting results
* Complete coverage of all major test designs and their limitations and advantages
* Current status of alternative test designs and models
Details
ISBN
978-0-12-272250-9
Language
English
Published
1998
Copyright
Copyright © 1998 Elsevier Inc. All rights reserved
Imprint
Academic Press