Cover for Gap Junction Structure and Chemical Regulation

Gap Junction Structure and Chemical Regulation

Direct Calmodulin Role in Cell-To-cell Channel Gating

Book2019

Authors:

Camillo Peracchia

Gap Junction Structure and Chemical Regulation

Direct Calmodulin Role in Cell-To-cell Channel Gating

Book2019

 

Cover for Gap Junction Structure and Chemical Regulation

Authors:

Camillo Peracchia

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Book description

Gap Junction Structure and Chemical Regulation: Direct Calmodulin Role in Cell-to-Cell Channel Gating describes and discusses the findings of major studies conducted during the pas ... read full description

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  2. Book chapterAbstract only

    Chapter 1 - Historical Background

    Pages 1-10

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    Chapter 2 - Ultrastructure

    Pages 11-33

  4. Book chapterAbstract only

    Chapter 3 - Molecular Structure

    Pages 35-43

  5. Book chapterAbstract only

    Chapter 4 - Chemical Gating—I. Role of Intracellular Calcium and Hydrogen Ions

    Pages 45-77

  6. Book chapterAbstract only

    Chapter 5 - Chemical Gating—II. Direct Calmodulin Role

    Pages 79-129

  7. Book chapterAbstract only

    Chapter 6 - Chemical Gating—III. Models

    Pages 131-164

  8. Book chapterAbstract only

    Chapter 7 - Connexin-Related Diseases

    Pages 165-170

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    Chapter 8 - Future Perspectives

    Pages 171-175

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    Further Reading

    Page 177

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    References

    Pages 179-203

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    Index

    Pages 205-212

About the book

Description

Gap Junction Structure and Chemical Regulation: Direct Calmodulin Role in Cell-to-Cell Channel Gating describes and discusses the findings of major studies conducted during the past century on the structure and chemical regulation of direct cell-to-cell communication via gap junction channels. Chapters bring together important findings on direct cell communication, from its history, to its structure and regulation. These channels are essential for normal organ function, and mutations in their protein (connexin) cause various diseases. The book is useful for established investigators who need a review on the field and young investigators who need a thorough resource for study and comprehension.

Gap Junction Structure and Chemical Regulation: Direct Calmodulin Role in Cell-to-Cell Channel Gating describes and discusses the findings of major studies conducted during the past century on the structure and chemical regulation of direct cell-to-cell communication via gap junction channels. Chapters bring together important findings on direct cell communication, from its history, to its structure and regulation. These channels are essential for normal organ function, and mutations in their protein (connexin) cause various diseases. The book is useful for established investigators who need a review on the field and young investigators who need a thorough resource for study and comprehension.

Key Features

  • Contains comprehensive, historical coverage on direct cell-to-cell communication
  • Provides detailed coverage of gap junction channel structure and regulation, with extensive coverage of the direct role of calmodulin in channel gating
  • Delivers a thorough description of models proposed for the chemical gating of gap junction channels
  • Contains comprehensive, historical coverage on direct cell-to-cell communication
  • Provides detailed coverage of gap junction channel structure and regulation, with extensive coverage of the direct role of calmodulin in channel gating
  • Delivers a thorough description of models proposed for the chemical gating of gap junction channels

Details

ISBN

978-0-12-816150-0

Language

English

Published

2019

Copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Imprint

Academic Press

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Authors

Camillo Peracchia

Professor Emeritus, Department of Pharmacology and Physiology, University of Rochester, School of Medicine and Dentistry, Rochester, NY, United States