Cover for Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

Volume 12

Book2018

Edited by:

M.A. Hayat

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

Volume 12

Book2018

 

Cover for Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

Edited by:

M.A. Hayat

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Book description

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 12 discusses and details almost all aspects of the autophagy machinery in the context of ... read full description

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  1. Full text access
  2. Book chapterAbstract only

    Chapter 1 - Overview of Autophagy

    M.A. Hayat

    Pages 1-122

  3. Book chapterAbstract only

    Chapter 2 - The Role of Autophagy in Aging: Molecular Mechanisms

    Maria Markaki, Athanasios Metaxakis and Nektarios Tavernarakis

    Pages 123-138

  4. Book chapterAbstract only

    Chapter 3 - The Role of p62 in Aggregopathies

    Estelle Cormet-Boyaka, Kyle Caution, ... Amal O. Amer

    Pages 139-147

  5. Book chapterAbstract only

    Chapter 4 - Role of Autophagy in the Transition From Monocyte to Differentiation

    Yan Zhang, Swati Choksi and Zhenggang Liu

    Pages 149-159

  6. Book chapterAbstract only

    Chapter 5 - Cdc48 AAA ATPase Regulates Protein Dynamics and Turnover in Mitochondria

    Masatoshi Esaki

    Pages 161-173

  7. Book chapterAbstract only

    Chapter 6 - Autophagy in Plasma Cells

    Niccolò Pengo and Simone Cenci

    Pages 175-186

  8. Book chapterAbstract only

    Chapter 7 - Loss of PINK1 or Parkin Function Results in a Progressive Loss of Mitochondrial Function

    Jan-Willem Taanman and Margherita Protasoni

    Pages 187-209

  9. Book chapterAbstract only

    Chapter 8 - Role of the Transcription Factor Interferon Regulatory Factor-1 in Regulating Autophagy in Lipopolysaccharide-Stimulated Macrophages

    Lemeng Zhang and Allan Tsung

    Pages 211-230

  10. Book chapterAbstract only

    Chapter 9 - Mechanistic Target of Rapamycin: The Alpha and Omega of Autophagy Regulation

    Olivia C. McKee-Muir and Ryan C. Russell

    Pages 231-250

  11. Book chapterAbstract only

    Chapter 10 - ER-Phagy in Starvation, ER Stress, and Quality Control

    Zhanna Lipatova and Nava Segev

    Pages 251-260

  12. Book chapterAbstract only

    Chapter 11 - Role of Autophagy Inhibition in Tumor Proliferative Arrest

    Jessie Yanxiang Guo

    Pages 261-274

  13. Book chapterAbstract only

    Chapter 12 - Survival at the Brink: Chromatin Autophagy of Tumor Cells in Response to Genotoxic Challenge

    Jekaterina Erenpreisa, Kristine Salmiņa, ... Mark S. Cragg

    Pages 275-294

  14. Book chapterAbstract only

    Chapter 13 - Loss of Autophagy in Hypothalamic Neurons May Be Involved in the Pathogenesis of Obesity

    Yenniffer Ávalos, María Paz Hernández-Cáceres, ... Eugenia Morselli

    Pages 295-312

  15. Book chapterAbstract only

    Chapter 14 - Defective Autophagy in Mesenteric Fat Tissue Maintains Inflammation in Crohn’s Disease

    Raquel F. Leal and Francesca A. Ramos Silva

    Pages 313-323

  16. Book chapterAbstract only

    Chapter 15 - Autophagy Regulates Inflammatory Responses in Antigen-Presenting Cells: Underlying Mechanisms

    James Harris, Tali Lang and Maria B. Sukkar

    Pages 325-341

  17. Book chapterAbstract only

    Chapter 16 - Autophagy Accompanies Inflammasome Activation to Moderate Inflammation by Eliminating Active Inflammasomes

    Neel R. Nabar, Chong-Shan Shi and John H. Kehrl

    Pages 343-357

  18. Book chapterAbstract only

    Chapter 17 - Autophagy, Inflammation, and Breast Cancer Risk

    Katherine L. Cook and Robert Clarke

    Pages 359-372

  19. Book chapterAbstract only

    Chapter 18 - AMBRA1-Mediated Regulation of C-MYC and Its Relevance to Cancer

    Valentina Cianfanelli and Francesco Cecconi

    Pages 373-385

  20. Book chapterAbstract only

    Chapter 19 - The Delicate Balance of Autophagy in Neurodegeneration

    Melissa Nassif, Ute Woehlbier and Patricio A. Manque

    Pages 387-399

  21. Book chapterAbstract only

    Chapter 20 - Silibinin Protects Ultraviolet B–Irradiated Skin by Balancing Apoptosis and Autophagy in Epidermis and Dermis

    Takashi Ikejima and Toshihiko Hayashi

    Pages 401-418

  22. Book chapterAbstract only

    Chapter 21 - Role of Autophagy Activation in Alleviating Alcohol Neurotoxicity

    Jia Luo

    Pages 419-434

  23. Book chapterAbstract only

    Chapter 22 - Lipopolysaccharide-Enhanced Bactericidal Activity is Mediated by Induction of the Autophagosomal Process

    Marc Y. Fink, Matthew R. Weichseldorfer, ... Michelle L. Snyder

    Pages 435-449

  24. Book chapterAbstract only

    Chapter 23 - Role of Autophagy in Liver Regeneration

    Takeo Toshima, Ken Shirabe, ... Yoshihiko Maehara

    Pages 451-461

  25. Book chapterAbstract only

    Chapter 24 - A Dual Role of a Soluble N-Ethylmaleimide Sensitive Factor–Attachment Protein Alpha (αSNAP) in the Regulation of Autophagy

    Andrei I. Ivanov

    Pages 463-472

  26. Book chapterAbstract only

    Chapter 25 - Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Induces Autophagic Protein Cleavage in Melanoma Cells

    Min You, Dao Nguyen, ... Niramol Savaraj

    Pages 473-487

  27. Book chapterNo access

    Abbreviations and Glossary

    Pages 489-501

  28. Book chapterNo access

    Index

    Pages 503-528

About the book

Description

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 12 discusses and details almost all aspects of the autophagy machinery in the context of health, cancer and other pathologies. Autophagy is more widely accepted as beneficial given its role in eliminating ‘toxic assets’ and promoting cell viability, hence, it has emerged as a new and potent modulator of disease progression that is both scientifically intriguing and clinically relevant. As the latest release in the Autophagy book series, users will find a detailed explanation of the role of molecular mechanisms.

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 12 discusses and details almost all aspects of the autophagy machinery in the context of health, cancer and other pathologies. Autophagy is more widely accepted as beneficial given its role in eliminating ‘toxic assets’ and promoting cell viability, hence, it has emerged as a new and potent modulator of disease progression that is both scientifically intriguing and clinically relevant. As the latest release in the Autophagy book series, users will find a detailed explanation of the role of molecular mechanisms.

Key Features

  • Presents the most advanced information regarding the role of the autophagic system in life and death
  • States recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities
  • Summarizes the most up-to-date findings on how autophagy is executed and regulated at the molecular level and how its disruption can lead to disease
  • Authored by global leaders in the field, bringing the broadest, most expert coverage available
  • Presents the most advanced information regarding the role of the autophagic system in life and death
  • States recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities
  • Summarizes the most up-to-date findings on how autophagy is executed and regulated at the molecular level and how its disruption can lead to disease
  • Authored by global leaders in the field, bringing the broadest, most expert coverage available

Details

ISBN

978-0-12-812146-7

Language

English

Published

2018

Copyright

Copyright © 2018 Elsevier Inc. All rights reserved.

Imprint

Academic Press

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Editors

M.A. Hayat

Distinguished Professor, Kean University, Union, NJ, United States