Cover for Aging, Sex, and DNA Repair

Aging, Sex, and DNA Repair

Book1991

Authors:

Carol Bernstein and Harris Bernstein

Aging, Sex, and DNA Repair

Book1991

 

Cover for Aging, Sex, and DNA Repair

Authors:

Carol Bernstein and Harris Bernstein

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Book description

Why organisms age and why sexual reproduction exists are major unsolved problems in biology. This book provides an integrated explanation of aging and sex based on current knowledg ... read full description

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  2. Book chapterNo access

    Chapter One - Introduction: Major Ideas and Historical Perspectives

    Pages 1-14

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    Chapter Two - DNA Damage

    Pages 15-26

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    Chapter Three - Immediate Consequences of DNA Damage

    Pages 27-36

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    Chapter Four - Accumulation of DNA Damage in Somatic Cells

    Pages 37-65

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    Chapter Five - The DNA Damage Hypothesis of Aging Applied to Mammals

    Pages 66-90

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    Chapter Six - Oxidative DNA Damage as a Potential Major Cause of Aging

    Pages 91-107

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    Chapter Seven - Additional Evidence Bearing on the DNA Damage Hypothesis of Aging

    Pages 108-151

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    Chapter Eight - Aging in Nonmammalian Organisms, with Comparisons to Aspects of Aging in Mammals

    Pages 152-172

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    Chapter Nine - DNA Repair with Emphasis on Single-Strand Damages

    Pages 173-207

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    Chapter Ten - DNA Repair with Emphasis on Recombinational Repair

    Pages 208-234

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    Chapter Eleven - Meiosis and Meiotic Recombination

    Pages 235-247

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    Chapter Twelve - Meiosis Viewed as an Adaptation for DNA Repair

    Pages 248-271

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    Chapter Thirteen - The Selective Advantage of Outcrossing

    Pages 272-289

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    Chapter Fourteen - Evolutionary Aspects of Sex

    Pages 290-312

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    Chapter Fifteen - Other Theories of Aging and Sex

    Pages 313-345

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    Chapter Sixteen - Overview, Future Directions, and Implications

    Pages 346-371

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    Subject Index

    Pages 373-382

About the book

Description

Why organisms age and why sexual reproduction exists are major unsolved problems in biology. This book provides an integrated explanation of aging and sex based on current knowledge of DNA damage and repair.

Why organisms age and why sexual reproduction exists are major unsolved problems in biology. This book provides an integrated explanation of aging and sex based on current knowledge of DNA damage and repair.

Key Features

  • Discusses the universality of the problem of DNA damage
  • Describes aging as a consequence of accumulated DNA damage
  • Considers meiosis as an adaptation for DNA repair
  • Discusses mating in eukaryotes as an adaptation for masking mutation
  • Discusses the universality of the problem of DNA damage
  • Describes aging as a consequence of accumulated DNA damage
  • Considers meiosis as an adaptation for DNA repair
  • Discusses mating in eukaryotes as an adaptation for masking mutation

Details

ISBN

978-0-12-092860-6

Language

English

Published

1991

Copyright

Copyright © 1991 Elsevier Inc. All rights reserved.

Imprint

Academic Press

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Authors

Carol Bernstein

Department of Microbiology and Immunology, College of Medicine, University of Arizona, Tucson, Arizona

Harris Bernstein

Department of Microbiology and Immunology, College of Medicine, University of Arizona, Tucson, Arizona